A critical and descriptive approach to interictal behavior with the Neurobehavior Inventory (NBI)

Epilepsy Behav. 2012 Nov;25(3):334-40. doi: 10.1016/j.yebeh.2012.08.031. Epub 2012 Oct 24.

Abstract

Purpose: The purpose of this study was to test the psychometric properties of the Neurobehavior Inventory (NBI) in a group of temporal lobe epilepsy (TLE) patients from a tertiary care center, correlating its scores with the presence of psychiatric symptoms.

Methods: Clinical and sociodemographic data from ninety-six TLE outpatients were collected, and a neuropsychiatric evaluation was performed with the following instruments: Mini-Mental State Examination (MMSE), structured psychiatric interview (MINI-PLUS), Neurobehavior Inventory (NBI), and Hamilton Depression Rating Scale (HAM-D).

Results: Some traits evaluated by the NBI showed adequate internal consistency (mean inter-item correlation between 0.2 and 0.4) and were frequent, such as religiosity (74%) and repetitiveness (60.4%). Principal component analysis showed three factors, named here as emotions (Factor 1), hyposexuality (Factor 2), and unusual ideas (Factor 3). Depressive symptoms on HAM-D showed a strong association with emotions and hyposexuality factors. When patients with left TLE and right TLE were compared, the former exhibited more sadness (p=0.017), and the latter, a greater tendency toward sense of personal destiny (p=0.028).

Conclusion: Depression influences NBI scoring, mainly emotionality and hyposexuality traits. Neurobehavior Inventory subscales can be better interpreted with an appropriate evaluation of comorbid mood and anxiety disorders. Compromise in left temporal mesial structures is associated with increased tendency toward sad affect, whereas right temporal pathology is associated with increased beliefs in personal destiny.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / epidemiology*
  • Cross-Sectional Studies
  • Epilepsy, Temporal Lobe / epidemiology*
  • Epilepsy, Temporal Lobe / psychology
  • Female
  • Humans
  • Male
  • Mental Disorders / diagnosis*
  • Mental Disorders / epidemiology
  • Middle Aged
  • Neuropsychological Tests*
  • Personality Disorders / epidemiology
  • Personality Inventory
  • Principal Component Analysis
  • Psychiatric Status Rating Scales
  • Young Adult