Task difficulty increases thresholds of rewarding brain stimulation

Behav Brain Res. 1990 Feb 12;37(1):1-7. doi: 10.1016/0166-4328(90)90066-n.

Abstract

The effect of increasing task difficulty on the threshold of rewarding, electrical brain stimulation was evaluated. Rats were trained to press a lever to obtain a brief burst of pulses to the lateral hypothalamus. The threshold was psychophysically scaled using a descending method of limits in which the pulse frequency was varied to yield a maximum to minimum range of self-stimulation rates. As expected, weighting the lever with 0, 15, 30, or 45 g produced progressive decreases in maximal rates, but it also caused a weight-related shift to the right of the rate-frequency ogives in each of the 7 rats. Although the degree of shift varied from rat to rat, it did not matter whether criterion performance was defined as half-maximum rate or as a constant rate of 5 responses. These results suggest that the effort required to make the operant response contributes to the position of rate-frequency curves and, further, that shifts in rate-frequency functions must be interpreted with caution when such shifts are obtained by CNS lesions or drug injections.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Arousal / physiology
  • Attention / physiology*
  • Conditioning, Operant / physiology*
  • Hypothalamic Area, Lateral / physiology*
  • Male
  • Motivation*
  • Physical Exertion / physiology*
  • Problem Solving / physiology
  • Rats
  • Rats, Inbred Strains
  • Self Stimulation / physiology*
  • Sensory Thresholds / physiology