Abstract
We report progress in the study of olive oil phenolic metabolites in humans and identify a new hydroxytyrosol metabolite called hydroxytyrosol acetate sulphate, which was determined using tandem MS, after ingestion of 30 ml of olive oil with a high phenolic content (500 mg/kg oil), reaching a maximum concentration of 1.63 μM. In order to understand and explain the generation of this metabolite, two different pathways are proposed.
Copyright © 2012 Elsevier Ltd. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Chromatography, High Pressure Liquid
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Humans
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Mass Spectrometry
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Metabolic Networks and Pathways
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Molecular Structure
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Olive Oil
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Phenols / analysis
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Phenols / metabolism
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Phenylethyl Alcohol / analogs & derivatives*
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Phenylethyl Alcohol / blood
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Phenylethyl Alcohol / chemistry
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Phenylethyl Alcohol / metabolism
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Plant Oils / analysis
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Plant Oils / metabolism*
Substances
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Olive Oil
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Phenols
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Plant Oils
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3,4-dihydroxyphenylethanol
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Phenylethyl Alcohol