Abstract
The polyketide synthase CTB1 is demonstrated to catalyze pyrone formation thereby expanding the known biosynthetic repertoire of thioesterase domains in iterative, non-reducing polyketide synthases.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Ascomycota / chemistry
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Ascomycota / enzymology*
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Ascomycota / metabolism
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Perylene / analogs & derivatives*
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Perylene / chemistry
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Perylene / metabolism
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Polyketide Synthases / chemistry
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Polyketide Synthases / metabolism*
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Protein Structure, Tertiary
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Pyrones / chemistry
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Pyrones / metabolism*
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Thiolester Hydrolases / chemistry
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Thiolester Hydrolases / metabolism
Substances
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Pyrones
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Perylene
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Polyketide Synthases
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cercosporin
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Thiolester Hydrolases