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. 2012 Oct 25;6:85.
doi: 10.3389/fncom.2012.00085. eCollection 2012.

Does Rhythmic Entrainment Represent a Generalized Mechanism for Organizing Computation in the Brain?

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Does Rhythmic Entrainment Represent a Generalized Mechanism for Organizing Computation in the Brain?

Kai J Miller et al. Front Comput Neurosci. .
Free PMC article

Figures

Figure 1
Figure 1
Generation of a simulated time series, with and without rhythmic entrainment. The illustrated heuristic was used to generate a 1/f base, broadband, synthetic time series that is entrained by a 15 Hz rhythm. The steps are numbered in the illustration: Poisson-distributed distal-dendrite synaptic inputs are each filtered by the shape of the post-synaptic current, and are integrated over space and time across the dendritic arbor. This summated input is then modulated by the frequency of proximal rhythmic inhibitory synaptic input. The timecourse of the current dipole potential is summated across many such model neurons. In accordance with experimental findings, periods of relative cortical “engagement” during task are devoid of the phase modulation of distal input, and periods of “disengagement” have phase modulation by the input rhythm. Aggregate rhythmic entrainment, revealed in the cross-frequency co-modulograms on the bottom right, shows significant entrainment during “disengagement,” and none during task “engagement.” Illustration and synthetic data construction adapted from Miller et al. (2010).

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