Occupation and leukemia in Nordic countries

J Occup Environ Med. 2012 Dec;54(12):1527-32. doi: 10.1097/JOM.0b013e3182664885.

Abstract

Objective: We studied occupational variation of the risk of acute myeloid leukemia, chronic lymphocytic leukemia, and other leukemia in Nordic countries.

Methods: The study cohort comprised 15 million persons older than 30 years who participated in the population censuses in 1960, 1970, 1980/1981, 1990, or all of these years in five Nordic countries. Standardized incidence ratios (SIRs) were estimated for 53 occupations and one group of economically inactive persons.

Results: Significantly increased risks were observed for acute myeloid leukemia among drivers (SIR = 1.16; 95% confidence interval [CI], 1.07-1.26) and food workers (SIR = 1.13; 95% CI, 1.01-1.27); for chronic lymphocytic leukemia among farmers (SIR = 1.09; 95% CI, 1.04-1.14) and clerical workers (SIR = 1.07; 95% CI, 1.01-1.14); and for other leukemia among seamen (SIR = 1.24; 95% CI, 1.04-1.49), "other health workers" (SIR = 1.22; 95% CI, 1.02-1.47), chemical process workers (SIR = 1.18; 95% CI, 1.01-1.38), and sales agents (SIR = 1.15; 95% CI, 1.06-1.25).

Conclusion: Observed modest occupational variation of leukemia risk might be associated with occupational or lifestyle factors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Female
  • Finland / epidemiology
  • Follow-Up Studies
  • Humans
  • Iceland / epidemiology
  • Incidence
  • Leukemia / epidemiology
  • Leukemia / etiology*
  • Male
  • Middle Aged
  • Occupational Diseases / epidemiology
  • Occupational Diseases / etiology*
  • Poisson Distribution
  • Regression Analysis
  • Risk Factors
  • Scandinavian and Nordic Countries / epidemiology