Diffuse esophageal spasm in children referred for manometry

J Pediatr Gastroenterol Nutr. 2013 Apr;56(4):436-8. doi: 10.1097/MPG.0b013e31827a7883.

Abstract

Diffuse esophageal spasm (DES) causes chest pain and/or dysphagia in adults. We reviewed charts of 278 subjects 0 to 18 years of age after esophageal manometry to describe the frequency and characteristics of DES in children. Patient diagnoses included normal motility (61%), nonspecific esophageal motility disorder (20%), DES (13%, n=36), and achalasia (4%). Of patients with DES, the most common chief complaint was food refusal in subjects younger than 5 years (14/24, 58%) and chest pain in subjects older than 5 years (4/12, 33%). Comorbid medical conditions, often multiple, existed in 33 subjects. DES should be considered when young children present with food refusal.

MeSH terms

  • Adolescent
  • Age Factors
  • Calcium Channel Blockers / therapeutic use
  • Chest Pain / etiology
  • Child
  • Child, Preschool
  • Cohort Studies
  • Comorbidity
  • Deglutition Disorders / etiology
  • Esophageal Achalasia / diagnosis
  • Esophageal Achalasia / epidemiology
  • Esophageal Achalasia / physiopathology
  • Esophageal Motility Disorders / diagnosis
  • Esophageal Motility Disorders / epidemiology
  • Esophageal Motility Disorders / physiopathology
  • Esophageal Spasm, Diffuse / diagnosis*
  • Esophageal Spasm, Diffuse / drug therapy
  • Esophageal Spasm, Diffuse / epidemiology
  • Esophageal Spasm, Diffuse / physiopathology
  • Esophagus / drug effects
  • Esophagus / physiopathology*
  • Feeding Behavior
  • Feeding and Eating Disorders / etiology
  • Feeding and Eating Disorders / prevention & control
  • Humans
  • Infant
  • Infant Behavior
  • Manometry
  • Nifedipine / therapeutic use
  • Retrospective Studies
  • Vomiting / etiology
  • Vomiting / prevention & control

Substances

  • Calcium Channel Blockers
  • Nifedipine