Abstract
Antibiotic impregnated articulating spacers are used in two-stage revision total knee arthroplasty to deliver local antibiotic therapy while preserving function. We have observed infection control in greater than 95% of cases with functional outcomes approaching those seen in revision for aseptic loosening. Higher failure has been observed with methicillin resistant organisms.
MeSH terms
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Anti-Bacterial Agents / administration & dosage*
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Anti-Bacterial Agents / therapeutic use
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Arthroplasty, Replacement, Knee / instrumentation*
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Arthroplasty, Replacement, Knee / methods
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Bone Cements
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Combined Modality Therapy
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Drug Delivery Systems*
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Follow-Up Studies
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Humans
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Knee Prosthesis / adverse effects*
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Prosthesis-Related Infections / drug therapy
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Prosthesis-Related Infections / surgery*
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Reoperation / instrumentation
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Reoperation / methods
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Treatment Outcome
Substances
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Anti-Bacterial Agents
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Bone Cements