Articulating antibiotic impregnated spacers in two-stage revision of infected total knee arthroplasty

J Bone Joint Surg Br. 2012 Nov;94(11 Suppl A):123-5. doi: 10.1302/0301-620X.94B11.30747.

Abstract

Antibiotic impregnated articulating spacers are used in two-stage revision total knee arthroplasty to deliver local antibiotic therapy while preserving function. We have observed infection control in greater than 95% of cases with functional outcomes approaching those seen in revision for aseptic loosening. Higher failure has been observed with methicillin resistant organisms.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / administration & dosage*
  • Anti-Bacterial Agents / therapeutic use
  • Arthroplasty, Replacement, Knee / instrumentation*
  • Arthroplasty, Replacement, Knee / methods
  • Bone Cements
  • Combined Modality Therapy
  • Drug Delivery Systems*
  • Follow-Up Studies
  • Humans
  • Knee Prosthesis / adverse effects*
  • Prosthesis-Related Infections / drug therapy
  • Prosthesis-Related Infections / surgery*
  • Reoperation / instrumentation
  • Reoperation / methods
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Bone Cements