Editorial: Proteostenosis: cancer's Achilles heel?

J Leukoc Biol. 2012 Nov;92(5):913-5. doi: 10.1189/jlb.0612272.

Abstract

Discussion on how defining protein synthesis vs. degradation rate may provide new directions in anti-cancer therapy.

Publication types

  • Editorial
  • Research Support, N.I.H., Intramural
  • Comment

MeSH terms

  • Animals
  • Cell Differentiation / drug effects*
  • Humans
  • Plasma Cells / metabolism*
  • Proteasome Endopeptidase Complex / metabolism*
  • Proteasome Inhibitors / pharmacology*
  • Protein Biosynthesis / drug effects*

Substances

  • Proteasome Inhibitors
  • Proteasome Endopeptidase Complex