An evaluation of 'Ribolola': a household tuberculosis contact tracing programme in North West Province, South Africa

Int J Tuberc Lung Dis. 2012 Dec;16(12):1643-8. doi: 10.5588/ijtld.12.0074.

Abstract

Setting: Rural/peri-urban community, South Africa.

Objectives: To examine the yield of tuberculosis (TB) cases, TB preventive therapy (TBPT) initiation and human immunodeficiency virus (HIV) diagnoses from household TB contact tracing.

Design: Retrospective programme analysis.

Methods: Households of index TB cases were visited and their contacts screened for TB and HIV. TB suspects provided sputum or were referred for assessment. Contacts aged <5 years were referred for assessment for TBPT initiation.

Results: There were 732 index TB cases (67.1% HIV-positive). Among 3627 household contacts, 3573 (98.5%) had known outcomes, of which 183 (5.0%) were already on appropriate treatment. Among 3390 remaining contacts, 361 (10.6%) were aged <5 years, of whom 34 (9.4%) started anti-tuberculosis treatment and 286 (79.2%) started TBPT. Among 3029 contacts aged ≥5 years, 93 (3.1%) started anti-tuberculosis treatment: 19 (20.4%) were smear-positive and 71 (76.3%) were culture-positive. Among contacts aged ≥14 years, 794/2133 (37.2%) underwent HIV testing, of whom 208/794 (26.2%) tested positive.

Conclusions: Household active case finding in this high TB and HIV prevalence setting obtained high yields of TB, particularly in those aged <5 years, and facilitated assessment for TBPT. There was a good yield of new HIV diagnoses, and a gain in efficiency due to integration within one programme.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antitubercular Agents / therapeutic use
  • Chi-Square Distribution
  • Child
  • Child, Preschool
  • Coinfection / diagnosis
  • Coinfection / epidemiology
  • Contact Tracing / methods*
  • Feasibility Studies
  • Female
  • HIV Infections / diagnosis
  • HIV Infections / epidemiology
  • Housing*
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Mycobacterium tuberculosis / isolation & purification
  • Odds Ratio
  • Predictive Value of Tests
  • Prevalence
  • Prognosis
  • Program Evaluation
  • Referral and Consultation
  • Retrospective Studies
  • South Africa / epidemiology
  • Sputum / microbiology
  • Time Factors
  • Tuberculosis, Pulmonary / diagnosis*
  • Tuberculosis, Pulmonary / epidemiology
  • Tuberculosis, Pulmonary / prevention & control
  • Tuberculosis, Pulmonary / transmission*
  • Young Adult

Substances

  • Antitubercular Agents