This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!

Skip to main page content

Email citation

Add to Collections

Your saved search

Name of saved search:

Search terms:

Test search terms

Would you like email updates of new search results?

Yes
No

Email: (change)

Frequency:

Which day?

Which day?

Report format:

Send at most:

Send even when there aren't any new results

Optional text in email:

Your RSS Feed

Review

. 2012 Nov 6:345:e7325.

doi: 10.1136/bmj.e7325.

Use of Mendelian randomisation to assess potential benefit of clinical intervention

Stephen Burgess¹, Adam Butterworth, Anders Malarstig, Simon G Thompson

Affiliations

Affiliation

¹ Strangeways Research Laboratory, Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK. sb452@medschl.cam.ac.uk

PMID: 23131671
DOI: 10.1136/bmj.e7325

Review

Use of Mendelian randomisation to assess potential benefit of clinical intervention

Stephen Burgess et al. BMJ. 2012.

. 2012 Nov 6:345:e7325.

doi: 10.1136/bmj.e7325.

Authors

Stephen Burgess¹, Adam Butterworth, Anders Malarstig, Simon G Thompson

Affiliation

¹ Strangeways Research Laboratory, Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK. sb452@medschl.cam.ac.uk

PMID: 23131671
DOI: 10.1136/bmj.e7325

No abstract available

PubMed Disclaimer

Similar articles

An introduction to instrumental variables--part 2: Mendelian randomisation.
Bennett DA. Bennett DA. Neuroepidemiology. 2010;35(4):307-10. doi: 10.1159/000321179. Epub 2010 Oct 29. Neuroepidemiology. 2010. PMID: 21042034
Interpretation of Mendelian randomization studies and the search for causal pathways in atherothrombosis: the need for caution.
Ridker PM, Paynter NP, Danik JS, Glynn RJ. Ridker PM, et al. Metab Syndr Relat Disord. 2010 Dec;8(6):465-9. doi: 10.1089/met.2010.0071. Epub 2010 Sep 6. Metab Syndr Relat Disord. 2010. PMID: 20818971 No abstract available.
[Mendelian randomisation - a genetic approach to an epidemiological method].
Stensrud MJ. Stensrud MJ. Tidsskr Nor Laegeforen. 2016 Jun 21;136(11):1002-5. doi: 10.4045/tidsskr.15.1262. eCollection 2016 Jun. Tidsskr Nor Laegeforen. 2016. PMID: 27325033 Review. Norwegian.
Severity of bias of a simple estimator of the causal odds ratio in Mendelian randomization studies.
Harbord RM, Didelez V, Palmer TM, Meng S, Sterne JA, Sheehan NA. Harbord RM, et al. Stat Med. 2013 Mar 30;32(7):1246-58. doi: 10.1002/sim.5659. Epub 2012 Oct 18. Stat Med. 2013. PMID: 23080538
Confounding in health research.
Greenland S, Morgenstern H. Greenland S, et al. Annu Rev Public Health. 2001;22:189-212. doi: 10.1146/annurev.publhealth.22.1.189. Annu Rev Public Health. 2001. PMID: 11274518 Review.

See all similar articles

Cited by

Association between high-density lipoprotein cholesterol and type 2 diabetes mellitus: dual evidence from NHANES database and Mendelian randomization analysis.
Yan Z, Xu Y, Li K, Liu L. Yan Z, et al. Front Endocrinol (Lausanne). 2024 Feb 22;15:1272314. doi: 10.3389/fendo.2024.1272314. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38455653 Free PMC article.
Evaluate the Relationship Between Obstructive Sleep Apnea and Metabolic Syndrome in Real-World Data.
Tang R, Li C, Di D, Zhou L, Qian Y, Qiang C, Ma C, Zhou R, Wang B, Wang M. Tang R, et al. Nat Sci Sleep. 2024 Feb 28;16:217-231. doi: 10.2147/NSS.S433514. eCollection 2024. Nat Sci Sleep. 2024. PMID: 38445023 Free PMC article.
Connecting atrial fibrillation to digestive neoplasms: exploring mediation via ischemic stroke and heart failure in Mendelian randomization studies.
Xu Z, Rao X, Xing Y, Zhu Z, Yan L, Huang J, Zhang J, Zheng R. Xu Z, et al. Front Oncol. 2024 Feb 20;14:1301327. doi: 10.3389/fonc.2024.1301327. eCollection 2024. Front Oncol. 2024. PMID: 38444673 Free PMC article.
Endocrine and metabolic factors and the risk of idiopathic pulmonary fibrosis: a Mendelian randomization study.
Jiang Y, Chen R, Xu S, Ding Y, Zhang M, Bao M, He B, Li S. Jiang Y, et al. Front Endocrinol (Lausanne). 2024 Jan 8;14:1321576. doi: 10.3389/fendo.2023.1321576. eCollection 2023. Front Endocrinol (Lausanne). 2024. PMID: 38260151 Free PMC article.
Increased fruit intake is associated with reduced risk of depression: evidence from cross-sectional and Mendelian randomization analyses.
Yan Z, Xu Y, Li K, Liu L. Yan Z, et al. Front Public Health. 2023 Dec 13;11:1276326. doi: 10.3389/fpubh.2023.1276326. eCollection 2023. Front Public Health. 2023. PMID: 38155897 Free PMC article.

See all "Cited by" articles

Publication types

Actions
Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Grants and funding

RG/08/014/British Heart Foundation/United Kingdom

LinkOut - more resources

Full Text Sources
- HighWire
- Ovid Technologies, Inc.
Medical
- MedlinePlus Health Information