Antibodies from colostrum in oral immunotherapy

J Clin Chem Clin Biochem. 1990 Jan;28(1):19-23.

Abstract

An immunoglobulin preparation for oral use was prepared from pooled bovine colostrum from more than 100 animals. The preparation has high antibacterial antibody titres, and a high capacity for the neutralization of bacterial toxins. It is well tolerated and highly effective in the treatment of severe diarrhoea, e.g. in AIDS patients. The preparation is spray-dried and stable at 2-8 degrees C.

MeSH terms

  • Acquired Immunodeficiency Syndrome / therapy
  • Animals
  • Antibodies / immunology*
  • Antitoxins / analysis
  • Antitoxins / immunology
  • Bacteria / growth & development
  • Colostrum / immunology*
  • Drug Stability
  • Female
  • Humans
  • Immunoglobulin G / immunology
  • Immunoglobulin M / immunology
  • Immunotherapy*
  • Mice
  • Microbial Sensitivity Tests
  • Proteins / analysis

Substances

  • Antibodies
  • Antitoxins
  • Immunoglobulin G
  • Immunoglobulin M
  • Proteins