Unilateral posterior stromal keratitis possibly secondary to Lyme disease

Cornea. 2013 Feb;32(2):196-8. doi: 10.1097/ICO.0b013e318274d85d.

Abstract

Purpose: To report a case of Lyme disease presenting as unilateral posterior stromal keratitis in a pediatric patient.

Methods: Case report and review of available literature.

Results: A 13-year-old adolescent with unilateral painless blurry vision presented with prominent posterior corneal stromal haze. A positive Borrelia burgdorferi antibody enzyme immunoassay and Western blot analysis (9 of 10 reactive immunoglobulin G bands and 1 of 3 immunoglobulin M bands) confirmed the diagnosis. Treatment with oral antibiotics and topical corticosteroids were necessary for resolution.

Conclusions: Lyme disease may present as a unilateral posterior stromal keratitis, even in a pediatric population. Treatment requires both systemic and topical therapy.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / therapeutic use
  • Antibodies, Bacterial / blood
  • Blotting, Western
  • Borrelia burgdorferi / immunology*
  • Corneal Stroma / pathology*
  • Doxycycline / therapeutic use
  • Drug Therapy, Combination
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Immunoenzyme Techniques
  • Immunoglobulin G / immunology
  • Immunoglobulin M / immunology
  • Keratitis / diagnosis
  • Keratitis / drug therapy
  • Keratitis / etiology*
  • Lyme Disease / complications*
  • Lyme Disease / drug therapy
  • Lyme Disease / immunology
  • Prednisolone / analogs & derivatives
  • Prednisolone / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Antibodies, Bacterial
  • Glucocorticoids
  • Immunoglobulin G
  • Immunoglobulin M
  • prednisolone acetate
  • Prednisolone
  • Doxycycline