Latent toxoplasmosis and human
Abstract
Toxoplasmosis is one of the most common parasitic diseases worldwide. Although estimated that one third of the world's population are infected with Toxoplasma gondii, but the most common form of the disease is latent (asymptomatic). On the other hand, recent findings indicated that latent toxoplasmosis is not only unsafe for human, but also may play various roles in the etiology of different mental disorders. This paper reviews new findings about importance of latent toxoplasmosis (except in immunocompromised patients) in alterations of behavioral parameters and also its role in the etiology of schizophrenia and depressive disorders, obsessive-compulsive disorder, Alzheimer's diseases and Parkinson's disease, epilepsy, headache and or migraine, mental retardation and intelligence quotients, suicide attempt, risk of traffic accidents, sex ratio and some possible mechanisms of T. gondii that could contribute in the etiology of these alterations.
Keywords: Behavioral parameter; Mental disorder; Toxoplasma gondii; Toxoplasmosis.
Similar articles
-
[Toxoplasma gondii: a potential role in the genesis of psychiatric disorders].Encephale. 2013 Feb;39(1):38-43. doi: 10.1016/j.encep.2012.06.014. Epub 2012 Aug 21. Encephale. 2013. PMID: 23095600 Review. French.
-
Neuropsychiatric manifestations of latent toxoplasmosis on mothers and their offspring.J Matern Fetal Neonatal Med. 2014 Sep;27(13):1368-74. doi: 10.3109/14767058.2013.858685. Epub 2013 Nov 26. J Matern Fetal Neonatal Med. 2014. PMID: 24156764 Review.
-
Toxoplasmosis impact on prematurity and low birth weight.PLoS One. 2022 Jan 13;17(1):e0262593. doi: 10.1371/journal.pone.0262593. eCollection 2022. PLoS One. 2022. PMID: 35025961 Free PMC article.
-
The potential risk of toxoplasmosis for traffic accidents: A systematic review and meta-analysis.Exp Parasitol. 2018 Aug;191:19-24. doi: 10.1016/j.exppara.2018.06.003. Epub 2018 Jun 12. Exp Parasitol. 2018. PMID: 29906469 Review.
-
Influence of latent Toxoplasma infection on human personality, physiology and morphology: pros and cons of the Toxoplasma-human model in studying the manipulation hypothesis.J Exp Biol. 2013 Jan 1;216(Pt 1):127-33. doi: 10.1242/jeb.073635. J Exp Biol. 2013. PMID: 23225875
Cited by
-
Latent toxoplasmosis, Cytomegalovirus, and Herpes Simplex Virus infections and risk of motorcycle accidents: A case-control study in a county with a high rate of motorcycle injuries in Iran.PLoS One. 2024 Aug 22;19(8):e0307950. doi: 10.1371/journal.pone.0307950. eCollection 2024. PLoS One. 2024. PMID: 39172983 Free PMC article.
-
Toxoplasma gondii infection and testosterone alteration: A systematic review and meta-analyses.PLoS One. 2024 Apr 3;19(4):e0297362. doi: 10.1371/journal.pone.0297362. eCollection 2024. PLoS One. 2024. PMID: 38568993 Free PMC article.
-
Relationship between Toxoplasma gondii infection and psychiatric disorders in Iran: A systematic review with meta-analysis.PLoS One. 2023 Aug 8;18(8):e0284954. doi: 10.1371/journal.pone.0284954. eCollection 2023. PLoS One. 2023. PMID: 37552680 Free PMC article.
-
Latent Toxoplasmosis among Breast Cancer Patients in Jahrom, South of Iran.Int J Breast Cancer. 2023 Jul 22;2023:4792260. doi: 10.1155/2023/4792260. eCollection 2023. Int J Breast Cancer. 2023. PMID: 37519423 Free PMC article.
-
Type-1 diabetes mellitus down-regulated local cerebral glial fibrillary acidic protein expression in experimental toxoplasmosis.J Parasit Dis. 2023 Jun;47(2):319-328. doi: 10.1007/s12639-023-01573-y. Epub 2023 Mar 18. J Parasit Dis. 2023. PMID: 37193484 Free PMC article.
References
-
- Montoya JM, Liesenfeld O. Toxoplasmosis. Lancet. 2004;363:1965–1976. - PubMed
-
- Hill D, Dubey JP. Toxoplasma gondii: transmission, diagnosis and prevention. Clin Microbiol Infect. 2002;8:634–640. - PubMed
-
- Bhopale GM. Pathogenesis of toxoplasmosis. Comp Immun Microbiol Infect Dis. 2003;26:213–222. - PubMed
-
- Maubon D, Ajzenberg D, Brenier-Pinchart MP, Darde ML, Pelloux H. What are the respective host and parasite contributions to toxoplasmosis? Trends Parasitol. 2008;24:299–303. - PubMed
LinkOut - more resources
Full Text Sources