Primary central nervous system histiocytic sarcoma

Brain Tumor Pathol. 2013 Jul;30(3):192-5. doi: 10.1007/s10014-012-0123-z. Epub 2012 Nov 8.

Abstract

Histiocytic sarcoma is a rare, lymphohematopoietic malignant neoplasm composed of tumor cells showing morphologic and immunophenotypic features of mature tissue histiocytes. Involvement of the central nervous system (CNS) as either a part of a systemic disease or as a primary lesion has rarely been described so far. We present a case of primary CNS histiocytic sarcoma in an adult patient and review the literature on this rare entity.

Publication types

  • Case Reports

MeSH terms

  • Brain / pathology
  • Brain Neoplasms / diagnosis*
  • Brain Neoplasms / pathology*
  • Brain Neoplasms / therapy
  • Diffusion Magnetic Resonance Imaging
  • Fatal Outcome
  • Histiocytic Sarcoma / diagnosis*
  • Histiocytic Sarcoma / pathology*
  • Histiocytic Sarcoma / therapy
  • Humans
  • Male
  • Middle Aged
  • Tomography, X-Ray Computed