The "skinny"on Sculptra: a practical primer to volumization with poly-L-lactic acid

J Drugs Dermatol. 2012 Sep;11(9):1046-52.


Poly-L-lactic acid (PLLA) is a biostimulatory agent that can correct bony and soft tissue facial deficiencies by producing gradual volume restoration. Proper patient selection and clear expectations are important to treatment success. Correct product preparation, injection technique, and patient follow-up correlates with increased patient safety, outcomes, and satisfaction. Alone, or in combination with other rejuvenative procedures, Sculptra® provides longer-lasting improvement to signs of facial aging.

MeSH terms

  • Adult
  • Aged
  • Collagen / metabolism
  • Cosmetic Techniques* / adverse effects
  • Female
  • Humans
  • Lactic Acid / administration & dosage*
  • Lactic Acid / adverse effects
  • Middle Aged
  • Patient Satisfaction
  • Patient Selection
  • Polyesters
  • Polymers / administration & dosage*
  • Polymers / adverse effects
  • Skin Aging*


  • Polyesters
  • Polymers
  • Lactic Acid
  • poly(lactide)
  • Collagen