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Review
. 2012 Sep;11(9):1059-68.

The Basic Science of Dermal Fillers: Past and Present Part I: Background and Mechanisms of Action

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  • PMID: 23135648
Review

The Basic Science of Dermal Fillers: Past and Present Part I: Background and Mechanisms of Action

Erin Gilbert et al. J Drugs Dermatol. .

Abstract

Dermal fillers have provided a safe and effective means for aesthetic soft tissue augmentation, and have experienced a dramatic increase in popularity during the past 10 years. Much focus has been placed upon filler technique and patient outcomes. However, there is a relative lack of literature reviewing the basic science of dermal fillers, which is vital to a physician's understanding of how each product behaves in vivo. Part I of this article reviews the basic science and evolution of both historical and contemporary dermal fillers; Part II examines their adverse effects. We endeavor to provide the physician with a practical approach to choosing products that maximize both aesthetic outcome and safety.

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