Using thermally regenerable cerium oxide nanoparticles in biocomputing to perform label-free, resettable, and colorimetric logic operations

Youhui Lin; Can Xu; Jinsong Ren; Xiaogang Qu

doi:10.1002/anie.201207587

Using thermally regenerable cerium oxide nanoparticles in biocomputing to perform label-free, resettable, and colorimetric logic operations

Angew Chem Int Ed Engl. 2012 Dec 7;51(50):12579-83. doi: 10.1002/anie.201207587. Epub 2012 Nov 7.

Authors

Youhui Lin¹, Can Xu, Jinsong Ren, Xiaogang Qu

Affiliation

¹ State Key laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.

PMID: 23136077
DOI: 10.1002/anie.201207587

Abstract

A label-free, resettable, and colorimetric logic network has been realized by utilizing thermally regenerable cerium oxide nanoparticles and biocatalytic reactions. Coupling switchable CeO(2) nanoparticles with biocomputing would convert molecular recognition events into colorimetric outputs and make logic gates feasible to reset.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Algorithms
Biocatalysis
Catalase / antagonists & inhibitors
Catalase / metabolism
Cerium / chemistry*
Colorimetry
Glucose Oxidase / antagonists & inhibitors
Glucose Oxidase / metabolism
Metal Nanoparticles / chemistry*
Temperature
Xanthine Oxidase / antagonists & inhibitors
Xanthine Oxidase / metabolism
beta-Galactosidase / antagonists & inhibitors
beta-Galactosidase / metabolism

Substances

Cerium
ceric oxide
Glucose Oxidase
Catalase
Xanthine Oxidase
beta-Galactosidase