A novel approach to the diagnosis of stress-induced cardiomyopathy

J Am Osteopath Assoc. 2012 Nov;112(11):743-7.


Stress-induced cardiomyopathy is becoming a more commonly recognized diagnosis, accounting for 2% to 3% of patients presenting with signs and symptoms of acute anterior myocardial infarction. We present the case of a 68-year-old man with dyspnea 9 days after an unrelated operation. After hospital admission, he complained of chest pain, and an electrocardiogram demonstrated ST-segment elevation in the anterolateral and inferior leads, ST-segment depression in lead aVR, and an absence of ST-segment changes in lead V(1). Cardiac biomarker levels were elevated. Transthoracic echocardiography demonstrated a left ventricular ejection fraction of 30% to 40%, basilar hyperactivity, apical dyskinesia, and distal inferior and anterior akinesia. Cardiac catheterization did not reveal any culprit obstructive lesion. He received a diagnosis of stress-induced cardiomyopathy and was treated according to established recommendations for systolic heart failure. His cardiac biomarkers returned to normal, and a repeated transthoracic echocardiogram 3 days later revealed nearly complete resolution of myocardial wall-motion abnormalities.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Blood Vessel Prosthesis Implantation / adverse effects
  • Heart Failure / diagnosis
  • Heart Failure / etiology
  • Heart Failure / therapy
  • Humans
  • Male
  • Stress, Psychological / complications
  • Takotsubo Cardiomyopathy / diagnosis*
  • Takotsubo Cardiomyopathy / etiology
  • Takotsubo Cardiomyopathy / therapy