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, 41 (Database issue), D605-12

EcoCyc: Fusing Model Organism Databases With Systems Biology

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EcoCyc: Fusing Model Organism Databases With Systems Biology

Ingrid M Keseler et al. Nucleic Acids Res.

Abstract

EcoCyc (http://EcoCyc.org) is a model organism database built on the genome sequence of Escherichia coli K-12 MG1655. Expert manual curation of the functions of individual E. coli gene products in EcoCyc has been based on information found in the experimental literature for E. coli K-12-derived strains. Updates to EcoCyc content continue to improve the comprehensive picture of E. coli biology. The utility of EcoCyc is enhanced by new tools available on the EcoCyc web site, and the development of EcoCyc as a teaching tool is increasing the impact of the knowledge collected in EcoCyc.

Figures

Figure 1.
Figure 1.
Biolog PM1 plate depicting E. coli carbon source utilization results from five different experiments under aerobic growth conditions.
Figure 2.
Figure 2.
The section of an EcoCyc gene page that provides gene essentiality information.

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