Nifedipine for intractable hiccups

Neurology. 1990 Mar;40(3 Pt 1):531-2. doi: 10.1212/wnl.40.3_part_1.531.


Seven patients with intractable hiccups were treated with a calcium channel blocker, nifedipine. A daily dose of 30 to 60 mg of this drug stopped hiccups in 4 patients and improved them in a 5th patient. In 2 patients hiccups recurred within 24 hours after stopping nifedipine. Nifedipine can be effective against intractable hiccups in some patients.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Hiccup / drug therapy*
  • Humans
  • Middle Aged
  • Nifedipine / administration & dosage
  • Nifedipine / therapeutic use*


  • Nifedipine