Methylxanthines and fibrocystic breast disease: a study of correlations

Nurse Pract. 1990 Mar;15(3):36-8, 43-4.


Daily methylxanthine ingestion from drug and dietary sources was studied by means of questionnaires from a sample of 102 women who visited the office of a radiologist for xeromammograms. The mammograms were used to measure the level of fibrocystic breast disease. Fibrocystic breast disease was found to be positively correlated with both caffeine and total methylxanthine ingestion. These positive findings are discussed in light of the fact that most recent studies of this link have been negative.

MeSH terms

  • Adult
  • Diet Surveys*
  • Female
  • Fibrocystic Breast Disease / chemically induced*
  • Fibrocystic Breast Disease / diagnostic imaging
  • Fibrocystic Breast Disease / pathology
  • Humans
  • Nutrition Surveys*
  • Radiography
  • Research Design
  • Xanthines / adverse effects*
  • Xanthines / pharmacology


  • Xanthines
  • methylxanthine