Statins inhibit in vitro virulence phenotypes of Pseudomonas aeruginosa

J Antibiot (Tokyo). 2013 Feb;66(2):99-101. doi: 10.1038/ja.2012.95. Epub 2012 Nov 14.

Authors

Emma Hennessy¹, Marlies J Mooij, Claire Legendre, F Jerry Reen, Julie O'Callaghan, Claire Adams, Fergal O'Gara

Affiliation

¹ Department of Microbiology, BIOMERIT Research Centre, University College Cork, Cork, Ireland.

PMID: 23149514
DOI: 10.1038/ja.2012.95

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / pharmacology*
Hydroxymethylglutaryl-CoA Reductase Inhibitors / pharmacology*
In Vitro Techniques
Lovastatin / analogs & derivatives
Lovastatin / pharmacology*
Microbial Sensitivity Tests
Phenotype
Pseudomonas aeruginosa / drug effects*
Pseudomonas aeruginosa / genetics
Pseudomonas aeruginosa / pathogenicity*
Virulence / genetics

Substances

Anti-Bacterial Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
mevastatin
Lovastatin