Cross-sectional imaging plays an important role in the evaluation of the retropharyngeal space (RPS) and the prevertebral space (PVS). Because of their deep location within the neck, lesions arising within these spaces are difficult, if not impossible, to evaluate on clinical examination. This article details the cross-sectional anatomy and imaging appearances of primary and secondary diseases involving the RPS and PVS, including metastasis and spread from adjacent spaces. The role of image-guided biopsy is also discussed.
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