Genital elephantiasis due to donovanosis: forgotten but not gone yet .

Int J STD AIDS. 2012 Nov;23(11):835-6. doi: 10.1258/ijsa.2012.012096.

Abstract

Genital elephantiasis is a disease that is characterized by massive enlargement of the genitalia. Early aetiological diagnosis is of paramount importance so that development of genital elephantiasis can be prevented; otherwise it is not completely reversible with medical therapy and often requires surgical intervention. Chronic mental distress and disability can result as it interferes with daily/routine activities of the affected individual. Over time, the infectious causes of genital elephantiasis have evolved, from syphilis in the pre-penicillin era to donovanosis, lymphogranuloma venereum and recently filariasis, tuberculosis, leishmaniasis, HIV and chromoblastomycosis. With a declining prevalence globally, donovanosis is at risk of being forgotten as a cause of genital swelling; however, it is known to persist for years without treatment and can lead to complications such as lymphoedema and genital mutilation. We herein present a case of genital elephantiasis that was eventually diagnosed as being due to donovanosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Elephantiasis / pathology*
  • Genitalia, Male / pathology*
  • Granuloma Inguinale / complications*
  • Granuloma Inguinale / pathology*
  • Histocytochemistry
  • Humans
  • Male
  • Microscopy