Intussusception due to inflammatory fibroid polyp: a case report and comprehensive literature review

World J Gastroenterol. 2012 Oct 28;18(40):5745-52. doi: 10.3748/wjg.v18.i40.5745.


Aim: To give an overview of the literature on intussusception due to inflammatory fibroid polyp (IFP).

Methods: We present a new case of ileal intussusception due to IFP and a literature review of studies published in English language on intussusception due to IFP, accessed via PubMed and Google Scholar databases. For the search, the keywords used were: intussusception, IFP, intussusception and IFP, intussusception due to IFP, and IFP presenting as intussusception. The search covered all articles from 1976 to November 2011.

Results: We present a 38-year-old woman who was admitted 10 d after experiencing abdominal pain, vomiting, and nausea. Ultrasonography demonstrated small bowel intussusception. An ileal intussusception due to a mass lesion 50 cm proximal to the ileocecal junction was found during laparotomy. Partial ileal resection and anastomosis were performed. A diagnosis of ileal IFP was made based on the immunohistochemical findings. In addition, a total of 56 reports concerning 85 cases of intussusception due to IFP meeting the aforementioned criteria was included in the literature review. The patients were aged 4 to 81 years (mean, 49 ± 16.2 years); 44 were women (mean, 51.8 ± 14.3 years) and 41 were men (mean, 46 ± 17.5 years). According to the location of the IFP, ileal intussusception was found in 63 patients, while 17 had jejunal, three had colonic, and two had ileojejunal intussusception.

Conclusion: Although IFPs are rare and benign, surgery is the only solution in case of intestinal obstruction. Differential diagnosis should be made via immunohistochemical examination.

Keywords: Immunohistochemical stain; Inflammatory fibroid polyp; Intussusception; Vanek’s tumor.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Ileal Diseases / diagnosis
  • Ileal Diseases / etiology*
  • Ileal Diseases / surgery
  • Ileitis / diagnosis
  • Ileitis / etiology*
  • Ileitis / surgery
  • Immunohistochemistry
  • Intestinal Polyps / complications*
  • Intestinal Polyps / diagnosis
  • Intestinal Polyps / surgery
  • Intussusception / diagnosis
  • Intussusception / etiology*
  • Intussusception / surgery
  • Male
  • Middle Aged
  • Young Adult