Possible induction of acute disseminated encephalomyelitis (ADEM)-like demyelinating illness by intrathecal mesenchymal stem cell injection

J Clin Neurosci. 2013 Feb;20(2):310-2. doi: 10.1016/j.jocn.2012.04.013. Epub 2012 Nov 14.


We report a 27-year-old woman with an episode of encephalitis and optic neuritis, followed by autologous bone marrow mesenchymal stem cell transplants and possible induction of acute disseminated encephalomyelitis-like demyelinating illness.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Encephalomyelitis, Acute Disseminated / diagnosis*
  • Encephalomyelitis, Acute Disseminated / etiology*
  • Encephalomyelitis, Acute Disseminated / surgery
  • Female
  • Humans
  • Injections, Spinal
  • Mesenchymal Stem Cell Transplantation / adverse effects*
  • Transplantation, Autologous / adverse effects