Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2012 Jul;9(4):489-94.

Dentinogenesis imperfecta associated with osteogenesis imperfecta

Affiliations
Case Reports

Dentinogenesis imperfecta associated with osteogenesis imperfecta

Mina Biria et al. Dent Res J (Isfahan). 2012 Jul.

Abstract

This paper presents a case with dentinogenesis imperfecta (DI) associated with osteogenesis imperfecta. Systemic and dental manifestations of OI and its medical and dental treatments are discussed in this paper. A 5-year-old child with the diagnosis of OI was referred to the Dental School of Shaid Beheshti University of Medical Sciences. On clinical examination yellow/brown discoloration of primary teeth with the attrition of the exposed dentin and class III malocclusion was observed. Enamel of first permanent molars was hypoplastic. Radiographic examinations confirmed the diagnosis of DI. A histological study was performed on one of the exfoliating teeth, which showed abnormal dentin. Primary teeth with DI were more severely affected compared to permanent teeth; enamel disintegration occurred in teeth with DI, demonstrating the need for restricts recalls for these patients.

Keywords: Brittle bone disease; dental anomalies; dentinogenesis imperfecta; osteogenesis imperfecta.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Bone deformity and the inserted rod in right and left femoral bone, respectively
Figure 2
Figure 2
Sagittal view of patient's face
Figure 3
Figure 3
Intraoral view. (a) Frontal view of the occlusion. (b) Occlusal view of the upper arch. (c) Occlusal view of the lower arch after placement of space maintainers. (d) Enamel disintegration on the right upper canine (a lateral view)
Figure 4
Figure 4
Panoramic radiography. Note the hypotrophic dentin and hypoplastic enamel on the first permanent molars
Figure 5
Figure 5
The patient received a face mask to stimulate the maxillary growth
Figure 6
Figure 6
Microscopic view of the sectioned tooth, (a) Periodic irregular dentinogenesis, (b) Dentin detachment, (c) Dentinogenesis with a globular pattern, (d) Interglobular pattern

Similar articles

Cited by

References

    1. Schwartz S, Tsipouras P. Oral findings in osteogenesis imperfecta. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1984;57:161–7. - PubMed
    1. Majorana A, Bardellini E, Brunelli PC, Lacaita M, Cazzolla AP, Favia G. Dentinogenesis imperfect in children with osteogenesis imperfecta: A clinical and ultrastructural study. Int J Paediatr Dent. 2010;20:112–8. - PubMed
    1. Germain-Lee EL. A new culprit in osteogenesis imperfect. J Bone Miner Res. 2011;26:2795–7. - PubMed
    1. Malmgren B, Norgren S. Dental aberrations in children and adolescents with osteogenesis imperfect. Acta Odontol Scand. 2002;60:65–71. - PubMed
    1. Sillence DO, Senn A, Danks DM. Genetic heterogeneity in osteogenesis imperfect. J Med Genet. 1979;16:101–6. - PMC - PubMed

Publication types

LinkOut - more resources