The antigen specific composition of melanoma tumor infiltrating lymphocytes?

Oncoimmunology. 2012 Sep 1;1(6):935-936. doi: 10.4161/onci.20303.


Large numbers of tumor associated antigens has been characterized, but only a minor fraction of these are recognized by tumor infiltrating lymphocytes of melanoma, although these have shown the ability to recognize tumor and provide tumor regression upon adoptive transfer. Thus the peptide recognition of the majority of the CD8 tumor infiltrating lymphocytes remains to be identified.