Ribosomally Synthesized and Post-Translationally Modified Peptide Natural Products: Overview and Recommendations for a Universal Nomenclature

Nat Prod Rep. 2013 Jan;30(1):108-60. doi: 10.1039/c2np20085f.

Abstract

This review presents recommended nomenclature for the biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs), a rapidly growing class of natural products. The current knowledge regarding the biosynthesis of the >20 distinct compound classes is also reviewed, and commonalities are discussed.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Biological Products* / chemical synthesis
  • Biological Products* / chemistry
  • Biological Products* / classification
  • Biological Products* / pharmacology
  • Humans
  • Molecular Sequence Data
  • Molecular Structure
  • Peptides* / chemical synthesis
  • Peptides* / chemistry
  • Peptides* / classification
  • Peptides* / pharmacology
  • Protein Processing, Post-Translational
  • Ribosomes / genetics
  • Ribosomes / metabolism*

Substances

  • Biological Products
  • Peptides