Prenatal and perinatal antecedents of febrile seizures

Ann Neurol. 1990 Feb;27(2):127-31. doi: 10.1002/ana.410270206.


We examined prenatal and perinatal characteristics as possible risk factors for febrile seizures in a large pediatric population. Family history was among the few identified factors that made an important contribution to vulnerability to febrile seizures; however, no more than 6% of febrile seizures could be attributed to a characteristic of family history. Maternal illness, smoking history, and a few rare neonatal characteristics were associated with increases in risk. No complication of labor or delivery was an important risk factor for febrile seizures.

MeSH terms

  • Anticonvulsants / adverse effects
  • Child, Preschool
  • Delivery, Obstetric
  • Family
  • Female
  • Glomerulonephritis / complications
  • Humans
  • Infant
  • Maternal Age
  • Obstetric Labor Complications
  • Pregnancy
  • Pregnancy Complications
  • Risk Factors
  • Seizures / complications
  • Seizures / drug therapy
  • Seizures, Febrile / epidemiology
  • Seizures, Febrile / etiology*
  • Smoking
  • Social Class


  • Anticonvulsants