Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 45 (1), 59-66

The Draft Genome of Sweet Orange (Citrus Sinensis)

Affiliations

The Draft Genome of Sweet Orange (Citrus Sinensis)

Qiang Xu et al. Nat Genet.

Abstract

Oranges are an important nutritional source for human health and have immense economic value. Here we present a comprehensive analysis of the draft genome of sweet orange (Citrus sinensis). The assembled sequence covers 87.3% of the estimated orange genome, which is relatively compact, as 20% is composed of repetitive elements. We predicted 29,445 protein-coding genes, half of which are in the heterozygous state. With additional sequencing of two more citrus species and comparative analyses of seven citrus genomes, we present evidence to suggest that sweet orange originated from a backcross hybrid between pummelo and mandarin. Focused analysis on genes involved in vitamin C metabolism showed that GalUR, encoding the rate-limiting enzyme of the galacturonate pathway, is significantly upregulated in orange fruit, and the recent expansion of this gene family may provide a genomic basis. This draft genome represents a valuable resource for understanding and improving many important citrus traits in the future.

Comment in

Similar articles

See all similar articles

Cited by 219 PubMed Central articles

See all "Cited by" articles

References

    1. Genome Biol. 2010;11(11):R116 - PubMed
    1. Bioinformatics. 2004 Jun 12;20(9):1453-4 - PubMed
    1. Trends Genet. 2007 Feb;23(2):60-6 - PubMed
    1. Trends Genet. 2001 Sep;17(9):536-40 - PubMed
    1. J Exp Bot. 2009;60(3):765-78 - PubMed

Publication types

Associated data

LinkOut - more resources

Feedback