Hormonal contraceptive continuation and switching in South Africa: implications for evaluating the association of injectable hormonal contraceptive use and HIV

J Acquir Immune Defic Syndr. 2013 Mar 1;62(3):363-5. doi: 10.1097/QAI.0b013e31827e818a.


Investigating the association between hormonal contraception and HIV is challenging due to high discontinuation rates among users. This secondary analysis of 262 South African adolescent new users of hormonal contraception found continuation rates after 1 year for depot medroxyprogesterone acetate, norethisterone enanthate, or combined oral contraceptives of 40.4%, 64.4%, and 64.6%, respectively. Implications for studies evaluating the association between injectable hormonal contraceptive use and HIV are discussed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Cohort Studies
  • Contraception Behavior / statistics & numerical data*
  • Contraceptive Agents, Female / administration & dosage*
  • Contraceptives, Oral, Hormonal / administration & dosage
  • Drug Substitution / statistics & numerical data*
  • Female
  • HIV Infections / prevention & control*
  • Humans
  • Injections
  • South Africa
  • Young Adult


  • Contraceptive Agents, Female
  • Contraceptives, Oral, Hormonal