Practical recommendations for the management of children with endemic Burkitt lymphoma (BL) in a resource limited setting

Pediatr Blood Cancer. 2013 Mar;60(3):357-62. doi: 10.1002/pbc.24407. Epub 2012 Nov 28.


Treatment recommendations for endemic Burkitt lymphoma (BL) in settings with only minimum requirements for curative treatment (PODC setting 1) are described. The reported cure rate for endemic BL is usually <50%. Facilities within setting 1 differ. Three treatment schedules are proposed based on: (1) when accurate staging is not possible, (2) when staging is possible and for (3) relapses and poor responders to primary therapy. A literature review and personal experience were used to formulate the recommendations. Recorded 1-year event free survival was 48% for treatment 1, 61% for treatment 2, and 35% for the rescue treatment.

Publication types

  • Practice Guideline

MeSH terms

  • Burkitt Lymphoma / diagnosis*
  • Burkitt Lymphoma / therapy*
  • Child
  • Developing Countries*
  • Health Resources*
  • Humans