Effects of Boswellic Acid of Boswellia Serrata and Other Triterpenic Acids on the Complement System

Phytomedicine. 1996 May;3(1):77-80. doi: 10.1016/S0944-7113(96)80016-X.


β-boswellic acid (BA), one major constituent of the resin of Boswellia serrata and other triterpenic acids of plant origin (crataegolic-, ursolic-, oleanolic- and glycyrrhetic acid) were found to possess anti-complementary activity in the classical and in the alternative complement pathway. Significant reduction of immunohemolysis in vitro was observed at BA concentrations between 0.005-0.1 mM with an IC(50) value of about 10 μmol/l.