Cross species integration of functional genomics experiments

Int Rev Neurobiol. 2012;104:1-24. doi: 10.1016/B978-0-12-398323-7.00001-X.


There is an increasing recognition of the value in integrating behavioral genomics data across species. The fragmentation of public resources, interoperability, and available representations present challenges due to the array of identifiers used to represent each genome feature. Once data are organized into a coherent collection, they can be integrated using a variety of methods to analyze convergent evidence for the roles of genes in behaviors. is a web-based software system that employs many of these techniques and has been used in the study of complex behavior and addiction. These techniques will be increasingly necessary to understand global patterns emerging from experiments in behavioral genomics.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Animals
  • Databases, Genetic*
  • Genomics*
  • Humans
  • Species Specificity
  • Systems Integration*