Laboratory testing for cytomegalovirus among pregnant women in the United States: a retrospective study using administrative claims data

BMC Infect Dis. 2012 Dec 3:12:334. doi: 10.1186/1471-2334-12-334.

Abstract

Background: Routine cytomegalovirus (CMV) screening during pregnancy is not recommended in the United States and the extent to which it is performed is unknown. Using a medical claims database, we computed rates of CMV-specific testing among pregnant women.

Methods: We used medical claims from the 2009 Truven Health MarketScan® Commercial databases. We computed CMV-specific testing rates using CPT codes.

Results: We identified 77,773 pregnant women, of whom 1,668 (2%) had a claim for CMV-specific testing. CMV-specific testing was significantly associated with older age, Northeast or urban residence, and a diagnostic code for mononucleosis. We identified 44 women with a diagnostic code for mononucleosis, of whom 14% had CMV-specific testing.

Conclusions: Few pregnant women had CMV-specific testing, suggesting that screening for CMV infection during pregnancy is not commonly performed. In the absence of national surveillance for CMV infections during pregnancy, healthcare claims are a potential source for monitoring practices of CMV-specific testing.

MeSH terms

  • Adolescent
  • Adult
  • Cytomegalovirus / pathogenicity*
  • Cytomegalovirus Infections / diagnosis*
  • Female
  • Humans
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis
  • Retrospective Studies
  • United States
  • Young Adult