Impact of country of birth on arterial function in subjects living in France

J Am Soc Hypertens. Nov-Dec 2012;6(6):405-13. doi: 10.1016/j.jash.2012.10.003.

Abstract

Affect of country of birth on arterial function in subjects (14,818 men and 9121 women) living in Paris but born in France or elsewhere in Europe (67%), Africa (25%), Asia (5%), and French Overseas Departments and Territories (3%) was investigated. Pulsatile hemodynamics involved central augmentation index (CAI) and central (carotid) pulse pressure (CPP). In African-born subjects compared with those born in France, age, blood pressure, overweight, and diabetes were factors associated with hypertension, but cardiovascular and renal impairment were absent. Asian-born subjects differed from others with lower body weight and high-density lipoprotein (HDL)-cholesterol, but higher plasma triglycerides and heart rate. Men's and women's pulsatile changes revealed significant interactions with CAI, and to a lesser extent with CPP, between gender and country of birth, particularly for African- and European-born subjects. For all the latter countries, increased cardiovascular risk of mortality, evaluated with Framingham scores, was highly significant but mainly for men. These data show that country-of-birth impact necessitated subdividing populations into men and women; at-risk populations were born in Africa, Asia, and Europe but less frequently in France; factors involving country-of-birth impact require further research on hereditary and environmental (frequently socioeconomic) factors but also geography and climate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Africa / ethnology
  • Asia / ethnology
  • Blood Pressure / physiology
  • Brachial Artery / physiology*
  • Cardiovascular Diseases / epidemiology*
  • Cholesterol / blood
  • Cohort Studies
  • Europe / ethnology
  • Female
  • France
  • Heart Rate / physiology
  • Humans
  • Male
  • Middle Aged
  • Risk Factors
  • Socioeconomic Factors
  • Triglycerides / blood

Substances

  • Triglycerides
  • Cholesterol