B regulatory cells in cancer

Trends Immunol. 2013 Apr;34(4):169-73. doi: 10.1016/j.it.2012.10.007. Epub 2012 Dec 1.


B regulatory cells are a newly described subpopulation of B cells that appear to play important roles in autoimmunity and more recently, in cancer. In this review we summarize our current knowledge of B regulatory cells, as well as the body of evidence pointing towards a role for B cells in general, and B regulatory cells in particular, in promoting tumor growth.

Publication types

  • Review

MeSH terms

  • Animals
  • Autoimmunity
  • B-Lymphocyte Subsets / immunology*
  • B-Lymphocytes, Regulatory / immunology*
  • Carcinogenesis
  • Humans
  • Immunomodulation
  • Neoplasms / immunology*