Pasting together the preventive therapy puzzle

Int J Tuberc Lung Dis. 2013 Feb;17(2):175-7. doi: 10.5588/ijtld.12.0230. Epub 2012 Dec 4.


In children, the effectiveness of preventive therapy (PT) for tuberculosis (TB) will always be dependent upon the care giver's behaviour, as this determines adherence. We briefly describe the knowledge, attitudes and intended behaviours in care givers of young children referred for PT in a resource-constrained setting with high TB rates. These early efforts describe one critical piece of the PT puzzle: uptake. More behavioural research is needed to understand how the many pieces of this puzzle should be assembled to improve PT usage in children.

Publication types

  • Comparative Study

MeSH terms

  • Antitubercular Agents / therapeutic use*
  • Child Behavior
  • Child, Preschool
  • Contact Tracing / methods*
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Latent Tuberculosis / epidemiology
  • Latent Tuberculosis / prevention & control*
  • Male
  • Morbidity / trends
  • Retrospective Studies
  • South Africa / epidemiology
  • Surveys and Questionnaires
  • Treatment Outcome


  • Antitubercular Agents