Patterns of systemic uptake of 18-FDG with positron emission tomography/computed tomography (PET/CT) studies in patients with presumed ocular tuberculosis

Ocul Immunol Inflamm. 2012 Dec;20(6):434-7. doi: 10.3109/09273948.2012.697596.


Aim: To report the patterns and sites of 18-FDG uptake in patients of presumed ocular tuberculosis.

Materials and methods: The clinical and investigational findings of 11 patients were reviewed retrospectively. These included 6 males and 5 females with a mean age of 46.2 years. 21 eyes were included in the data analysis. Clinical presentations include 15 eyes with anterior uveitis, 2 eyes with retinal vasculitis, 2 eyes with panuveitis and 2 eyes with multifocal choroidopathy.

Results: Two distinct patterns of systemic uptake emerged. Pattern 1: No detectable systemic uptake (4 patients). Pattern 2: Detectable systemic uptake. a. Chest disease only (2 patients). b. Disseminated pattern, uptake seen at multiple sites (4 patients). c. Extrapulmonary only (1 patient).

Conclusions: Ocular tuberculosis may often be part of a wider disseminated disease.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Diagnosis, Differential
  • Female
  • Fluorodeoxyglucose F18 / pharmacokinetics*
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Multimodal Imaging / methods*
  • Positron-Emission Tomography*
  • Radiopharmaceuticals / pharmacokinetics
  • Reproducibility of Results
  • Retrospective Studies
  • Tomography, X-Ray Computed*
  • Tuberculosis, Ocular / diagnosis*
  • Tuberculosis, Ocular / metabolism


  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18