Planar cell polarity: microtubules make the connection with cilia

Michael E Werner; Brian J Mitchell

doi:10.1016/j.cub.2012.10.030

Planar cell polarity: microtubules make the connection with cilia

Curr Biol. 2012 Dec 4;22(23):R1001-4. doi: 10.1016/j.cub.2012.10.030.

Authors

Michael E Werner¹, Brian J Mitchell

Affiliation

¹ Department of Cell and Molecular Biology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.

PMID: 23218005
DOI: 10.1016/j.cub.2012.10.030

Abstract

Despite decades of research there are still basic aspects of planar cell polarity that are not well understood. Recent work in mouse tracheal epithelial cells links microtubules with both establishing asymmetry as well as responding to this asymmetry to coordinate cellular orientation.

MeSH terms

Animals
Cell Polarity*
Cilia / physiology
Epithelial Cells / physiology
Mice
Microtubules / physiology
Respiratory Mucosa / physiology