Getting trichy: tools and approaches to interrogating Trichomonas vaginalis in a post-genome world

Trends Parasitol. 2013 Jan;29(1):17-25. doi: 10.1016/ Epub 2012 Dec 5.


Trichomonas vaginalis is a parasite of the urogenital tract in men and women, with a worldwide presence and significant implications for global public health. T. vaginalis research entered the age of genomics with the publication of the first genome sequence in 2007, but subsequent utilization of other 'omics' technologies and methods has been slow. Here, we review some of the tools and approaches available to interrogate T. vaginalis biology, with an emphasis on recent advances and current limitations, and draw attention to areas where further efforts are needed to examine effectively the complex and intriguing biology of the parasite.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Drug Resistance / genetics
  • Gene Expression Regulation
  • Genome / genetics*
  • Genomics
  • Humans
  • Metagenome
  • Parasitology / methods*
  • Trichomonas Infections / parasitology*
  • Trichomonas vaginalis / genetics*
  • Trichomonas vaginalis / virology