A new antibacterial phenanthrenequinone from Dendrobium sinense

J Asian Nat Prod Res. 2013;15(1):67-70. doi: 10.1080/10286020.2012.740473. Epub 2012 Dec 11.

Abstract

A new phenanthrenequinone, named denbinobin B (1), together with three known phenanthrenes was isolated from the whole plant of Dendrobium sinense T. Tang et F.T. Wang, an endemic and endangered orchid to Hainan Island. The new compound was elucidated using a combination of 1D, 2D NMR (COSY, HMQC, and HMBC) techniques, and HR-ESI-MS analyses. Compound 1 exhibited moderate antibacterial activity against Staphylococcus aureus with the diameter of the inhibition zone of 16.5 mm.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anthraquinones
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification
  • Anti-Bacterial Agents / pharmacology*
  • China
  • Dendrobium / chemistry*
  • Nuclear Magnetic Resonance, Biomolecular
  • Phenanthrenes / chemistry
  • Phenanthrenes / isolation & purification*
  • Phenanthrenes / pharmacology*
  • Staphylococcus aureus / drug effects

Substances

  • Anthraquinones
  • Anti-Bacterial Agents
  • Phenanthrenes
  • denbinobin
  • denbinobin B