MicroRNAs (miRNAs) are a class of short endogenous non-coding RNAs regulating gene expression in many biological processes, including proliferation, apoptosis and differentiation. The deregulation of miRNA expression is believed to be an important regulator of tumor development and progression of thyroid cancer. In this review, we discussed important roles and expression profiles of miRNA in differentiated thyroid cancer (DTC) as well as the promising implication in clinical practice.
Keywords: Differentiated thyroid cancer; fine needle aspiration biopsy; microRNA; mutations.