The soothing touch: microglial contact influences neuronal excitability

Aude Panatier; Richard Robitaille

doi:10.1016/j.devcel.2012.11.015

The soothing touch: microglial contact influences neuronal excitability

Dev Cell. 2012 Dec 11;23(6):1125-6. doi: 10.1016/j.devcel.2012.11.015.

Authors

Aude Panatier¹, Richard Robitaille

Affiliation

¹ INSERM U862, Neurocentre Magendie, 33077 Bordeaux, France; Université de Bordeaux, 33077 Bordeaux, France. aude.panatier@inserm.fr

PMID: 23237948
DOI: 10.1016/j.devcel.2012.11.015

Abstract

Resting microglial cells in the brain scan their environment with their processes, primed to react to injury and disease. In this issue of Developmental Cell, Li and colleagues (2012) report that resting microglia also react to physiological neuronal activity, sending their processes toward highly active neurons to regulate their excitability.

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