Abstract
We evaluated 13 workers with respiratory symptoms apparently related to occupational exposure to powdered rose hips. Nine workers had asthma, five had rhinitis, and one worker had urticaria. Seven workers had evidence of IgE specific for rose hips based on positive skin prick tests and positive in vitro tests. Four workers with histories suggestive of asthma related to work exposure underwent bronchopulmonary challenges with rose hips, and two workers had positive challenges with greater than 20% declines in FEV1 measurements. We conclude that rose hips are occupational allergens capable of producing asthma.
MeSH terms
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Adult
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Allergens / adverse effects*
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Allergens / immunology
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Antibody Specificity
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Ascorbic Acid / adverse effects*
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Ascorbic Acid / immunology
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Bronchial Provocation Tests
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Enzyme-Linked Immunosorbent Assay
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Female
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Humans
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Immunoglobulin E / analysis
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Male
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Occupational Diseases / etiology*
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Occupational Diseases / immunology
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Occupational Diseases / physiopathology
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Plant Extracts / adverse effects*
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Plant Extracts / immunology
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Powders
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Respiratory Hypersensitivity / etiology*
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Respiratory Hypersensitivity / immunology
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Respiratory Hypersensitivity / physiopathology
Substances
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Allergens
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Plant Extracts
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Powders
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Immunoglobulin E
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Ascorbic Acid