Psychiatric medications: adverse cutaneous drug reactions

Clin Dermatol. 2013 Jan-Feb;31(1):101-9. doi: 10.1016/j.clindermatol.2011.11.014.


Psychiatric medications are among the most widely prescribed medications in the United States. Adverse cutaneous drug reactions are associated with psychiatric medications in approximately 2% to 5% of the individuals for whom they are prescribed. Although most adverse cutaneous drug reactions associated with psychotropic medications are benign and easily treated, some can be disfiguring or life-threatening, particularly those associated with the mood stabilizers. Adverse cutaneous drug reactions associated with antidepressants, antipsychotics, and mood stabilizers are reviewed, and important issues that are of concern for the dermatologist who must consider when and how to safely discontinue a psychotropic medication in their patients are presented.

MeSH terms

  • Antipsychotic Agents / adverse effects*
  • Drug Eruptions / etiology*
  • Drug Hypersensitivity / etiology*
  • Humans
  • Practice Patterns, Physicians'
  • Psychotropic Drugs / adverse effects*
  • Skin Diseases / chemically induced*
  • Time Factors


  • Antipsychotic Agents
  • Psychotropic Drugs