¹H, ¹³C, and ¹⁵N chemical shift assignments of neuronal calcium sensor protein, hippocalcin

Biomol NMR Assign. 2014 Apr;8(1):63-6. doi: 10.1007/s12104-012-9453-3. Epub 2012 Dec 19.

Abstract

Hippocalcin, a member of the neuronal calcium sensor (NCS) subclass of the calmodulin superfamily, serves as an important calcium sensor for the slow afterhyperpolarizing (sAHP) current in the hippocampus, which underlies some forms of learning and memory. Hippocalcin is also a calcium sensor for hippocampal long-term depression (LTD) and genetically linked to neurodegenerative diseases. We report NMR chemical shift assignments of Ca(2+)-free hippocalcin (BMRB no. 18627).

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Amino Acid Sequence
  • Carbon Isotopes
  • Hippocalcin / chemistry*
  • Humans
  • Hydrogen
  • Molecular Sequence Data
  • Neuronal Calcium-Sensor Proteins / chemistry*
  • Neurons / metabolism*
  • Nitrogen Isotopes
  • Nuclear Magnetic Resonance, Biomolecular*
  • Sequence Alignment

Substances

  • Carbon Isotopes
  • HPCA protein, human
  • Neuronal Calcium-Sensor Proteins
  • Nitrogen Isotopes
  • Hippocalcin
  • Hydrogen