Adoption of rotavirus vaccine by U.S. physicians: progress and challenges

Am J Prev Med. 2013 Jan;44(1):56-62. doi: 10.1016/j.amepre.2012.10.001.


Background: Pentavalent rotavirus vaccine (RV5) was recommended for routine use in 2006 followed by monovalent rotavirus vaccine (RV1) in 2008.

Purpose: To describe, among a U.S. sample of pediatricians (n=289 respondents) and family medicine physicians (n=243 respondents), (1) current practices regarding rotavirus vaccine (RV) and barriers to use with comparison to a 2007 survey and (2) knowledge of recent safety concerns regarding RV1 and their impact on its use.

Methods: A mail and Internet survey was conducted with the physicians, from November 2010 to January 2011; analyses were conducted March-September 2011.

Results: Response rates were 70% (289/410) for pediatricians and 61% (243/401) for family medicine physicians; routine administration of RV was reported by 95% of pediatricians and 65% of family medicine physicians (2007: 85% and 45%). Almost all barriers to use of RV had decreased compared to 2007. For pediatricians and family medicine physicians, respectively, 94% and 70% were aware of the temporary suspension of RV1 due to presence of porcine circovirus; 49% and 45%, respectively, were aware of the addition to RV1 labeling regarding a possible increased risk of intussusception. Among physicians aware of the safety issues, <5% reported stopping giving RV as a result. After reading information about porcine circovirus, 35% of pediatricians and 59% of family medicine physicians reported it had increased their own concerns about the safety of RV; and 31% and 60%, respectively, reported this regarding intussusception.

Conclusions: The acceptance of RV has increased, and barriers to use have decreased. Among physicians, recent safety questions about RV1 have not affected use of RV, although they have raised safety concerns.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Attitude of Health Personnel*
  • Circovirus / isolation & purification
  • Drug Contamination
  • Female
  • Health Care Surveys
  • Humans
  • Intussusception / etiology
  • Male
  • Middle Aged
  • Pediatrics / statistics & numerical data
  • Physicians, Family / statistics & numerical data
  • Practice Patterns, Physicians' / statistics & numerical data*
  • Rotavirus Infections / prevention & control*
  • Rotavirus Vaccines / administration & dosage*
  • Rotavirus Vaccines / adverse effects
  • Rotavirus Vaccines / standards
  • Swine
  • United States


  • Rotavirus Vaccines